The use of cocaine is linked with the stress-related disorder. Recent studies have shown that the long-term exposure of cocaine in animals leads to glutamate neurotransmission changes for example, cocaine affects the amount of glutamate produced and its receptor protein levels. The consumption of cocaine leads to affect the pathways affiliated with stress in the brain. Its consumption also creates violent behavior, sexual arousal, euphoria, anxiety, energy, excitement, panic mode, restlessness, and irritability in consumers. The consumption of cocaine leads to short-term effects such as high temperature, increased heartbeat, and blood pressure. ![]() ![]() But when cocaine is smoked, the highness lasts for only five to ten minutes. When a person snorts cocaine, the highness lasts from 15 to 30 minutes. If the drug is absorbed faster, then the euphoric effects are very intensive but last for a shorter duration. This creates euphoria instantly after consuming the drug. This leads to the accumulation of dopamine in the synapse to generate an elaborated signal to the receiving part. For example, cocaine binds with a transporter protein and blocks the removal of dopamine from the synapse for recycling. Drugs like cocaine interfere with this communication process. Dopamine is removed from the synapse for recycling with the help of a specialized protein called transporter protein. Dopamine is a neurotransmitter released by a neuron that acts as a chemical messenger and passes information from the neurons present in the brain to the other parts of the body with the help of dopamine receptors. Neurotransmitters transmit signals from the nerve cell of neurons to the target cell. ![]() It affects the process of the brain and neural system. The recreational drug, otherwise known as a psychoactive drug, refers to the chemical substance that changes human mental health by changing the perceptions, feelings, and emotions of the user. Cocaine is also a powerful recreational drug. This results in more alertness, consciousness, confidence, and energy in individuals who consume the drug. The stimulant may speed up the process of transfer of information from the brain to the other parts of the body. The high doses of stimulants create feelings of aversion or fear, high temperature, and abnormal heartbeat.
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